A Handbook for DNA-Encoded Chemistry

A Handbook for DNA-Encoded Chemistry

Robert A. Goodnow, Jr.

This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

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ISBN-10: 1-118-83269-8

ISBN-13: 978-1-118-83269-1

Язык книги: en

Возрастные ограничения: 0+

Издательсто: John Wiley & Sons Limited
Категория: Химия